Xiaodong Sun Selected Research

RNA (Ribonucleic Acid)

12/2023	Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b+ Ly6G+ Cells and Increasing the Viral Load in the Cornea.
2/2023	PFKFB3 knockdown attenuates Amyloid β-Induced microglial activation and retinal pigment epithelium disorders in mice.
1/2022	A novel and efficient murine model of Bietti crystalline dystrophy.
1/2021	Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice.
5/2020	CasRx-mediated RNA targeting prevents choroidal neovascularization in a mouse model of age-related macular degeneration.
12/2019	Intraocular VEGF deprivation induces degeneration and fibrogenic response in retina.
5/2012	Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer.
8/2009	Down-regulation of tumor suppressor gene FEZ1/LZTS1 in breast carcinoma involves promoter methylation and associates with metastasis.

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Xiaodong Sun Research Topics

Disease

70	Neoplasms (Cancer) 05/2024 - 04/2004
39	Macular Degeneration (Age-Related Maculopathy) 05/2024 - 10/2012
30	Inflammation (Inflammations) 04/2024 - 09/2004
24	Choroidal Neovascularization 01/2024 - 09/2011
19	Obesity 03/2023 - 02/2012
19	Retinal Detachment (Retinal Detachments) 02/2023 - 09/2007
17	Carcinogenesis 04/2024 - 04/2003
16	Breast Neoplasms (Breast Cancer) 01/2024 - 02/2007
12	Infections 01/2024 - 10/2010
12	Diabetic Retinopathy (Retinopathy, Diabetic) 02/2023 - 04/2009
11	Neoplasm Metastasis (Metastasis) 08/2023 - 05/2012
11	Malaria 08/2022 - 10/2010
10	Macular Edema 12/2023 - 08/2012
10	Glaucoma 12/2023 - 08/2014
10	Prostatic Neoplasms (Prostate Cancer) 07/2015 - 04/2005
9	Fibrosis (Cirrhosis) 01/2023 - 09/2014
8	Hypoxia (Hypoxemia) 01/2023 - 04/2016
7	Blindness (Hysterical Blindness) 11/2023 - 01/2015
7	COVID-19 10/2023 - 01/2021
7	Non-alcoholic Fatty Liver Disease 04/2023 - 01/2020
6	Body Weight (Weight, Body) 04/2024 - 11/2012
6	Type 2 Diabetes Mellitus (MODY) 04/2024 - 06/2011
6	Retinal Diseases 02/2024 - 03/2014
6	Myopia 12/2023 - 08/2015
6	Insulin Resistance 10/2023 - 06/2011
6	Polypoidal Choroidal Vasculopathy 01/2022 - 01/2015
5	Neuroinflammatory Diseases 01/2024 - 01/2021
5	Epiretinal Membrane (Epiretinal Membranes) 09/2023 - 08/2015
5	Retinal Degeneration 01/2022 - 01/2017
5	Heart Failure 01/2019 - 03/2011
4	Retinitis Pigmentosa (Pigmentary Retinopathy) 02/2024 - 01/2021
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2024 - 01/2020
4	Colorectal Neoplasms (Colorectal Cancer) 04/2023 - 09/2008
4	Retinal Vein Occlusion 10/2022 - 01/2013
4	Pneumonia (Pneumonitis) 04/2022 - 06/2017
4	Measles 01/2022 - 11/2014
4	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2021 - 11/2020
4	Ganglion Cysts (Ganglion) 01/2020 - 09/2007
4	Myocardial Infarction 01/2020 - 09/2014
4	Hemorrhage 01/2020 - 02/2016
4	Gliosis 12/2019 - 01/2008
4	Cardiovascular Diseases (Cardiovascular Disease) 12/2019 - 04/2014
4	Lymphatic Metastasis 03/2018 - 08/2009
4	Pancreatic Neoplasms (Pancreatic Cancer) 10/2017 - 10/2012
4	Neovascular Glaucoma 02/2016 - 12/2015
3	Atrophy 05/2024 - 01/2023
3	Wounds and Injuries (Trauma) 04/2024 - 04/2014

Drug/Important Bio-Agent (IBA)

39	Proteins (Proteins, Gene)FDA Link 01/2024 - 05/2005
35	Retinaldehyde (Retinal)IBA 05/2024 - 09/2007
28	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2023 - 04/2009
19	VaccinesIBA 02/2024 - 02/2012
17	Messenger RNA (mRNA)IBA 01/2023 - 04/2005
13	Transcription Factors (Transcription Factor)IBA 12/2021 - 04/2003
12	LipidsIBA 11/2023 - 06/2011
8	EnzymesIBA 01/2024 - 02/2009
8	RNA (Ribonucleic Acid)IBA 12/2023 - 08/2009
8	Glucose (Dextrose)FDA LinkGeneric 10/2023 - 06/2011
8	CytokinesIBA 01/2023 - 10/2010
7	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2014
6	Retinal Pigments (Pigments, Visual)IBA 02/2024 - 01/2018
6	KH902 fusion proteinIBA 11/2023 - 01/2015
6	MicroRNAs (MicroRNA)IBA 02/2023 - 01/2017
6	empagliflozinIBA 01/2023 - 01/2020
6	AdiponectinIBA 01/2022 - 10/2014
6	DNA (Deoxyribonucleic Acid)IBA 09/2021 - 04/2008
6	Bevacizumab (Avastin)FDA Link 02/2016 - 01/2011
5	LigandsIBA 10/2023 - 04/2012
5	Amyloid (Amyloid Fibrils)IBA 03/2023 - 12/2018
5	Therapeutic UsesIBA 01/2023 - 07/2006
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2015 - 10/2010
5	cytoplasmic linker protein 170 (restin)IBA 04/2014 - 03/2012
4	7,3'-dihydroxy-4'-methoxyisoflavoneIBA 05/2024 - 04/2018
4	Amino Acids FDA Link 04/2024 - 01/2022
4	Doxorubicin (Adriamycin)FDA LinkGeneric 03/2024 - 06/2017
4	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 01/2024 - 06/2017
4	AntioxidantsIBA 04/2023 - 06/2011
4	Circular RNAIBA 01/2023 - 11/2022
4	Nonesterified Fatty Acids (NEFA)IBA 11/2022 - 08/2013
4	AlbuminsIBA 11/2022 - 01/2013
4	Cisplatin (Platino)FDA LinkGeneric 08/2022 - 02/2015
4	CollagenIBA 08/2022 - 05/2010
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 04/2009
4	Peptides (Polypeptides)IBA 01/2022 - 11/2009
4	Ranibizumab (Lucentis)FDA Link 01/2020 - 08/2012
4	artemisinin (artemisinine)IBA 02/2016 - 08/2012
4	Fenofibrate (CiL)FDA LinkGeneric 10/2013 - 02/2012
4	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2013 - 12/2005
4	Kruppel-Like Transcription Factors (Kruppel-Like Factors)IBA 01/2010 - 04/2003
3	afliberceptIBA 05/2024 - 01/2020

Therapy/Procedure

38	Therapeutics 04/2024 - 02/2009
13	Drug Therapy (Chemotherapy) 03/2024 - 03/2012
12	Lasers (Laser) 01/2024 - 05/2012
9	Aftercare (After-Treatment) 01/2022 - 04/2012
7	Intravitreal Injections 11/2023 - 09/2007
7	Vitrectomy 02/2023 - 02/2013
7	Liver Transplantation 01/2023 - 03/2018
5	Radiotherapy 01/2022 - 02/2015
5	Transplantation 03/2018 - 05/2010
4	Immunotherapy 02/2024 - 01/2018
4	Chinese Traditional Medicine (Traditional Chinese Medicine) 11/2023 - 01/2018